2RJH

Crystal structure of biosynthetic alaine racemase in D-cycloserine-bound form from Escherichia coli

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Alanine racemase	polymer	379	41416.2	4	UniProt (P0A6B4) Pfam (PF01168) Pfam (PF00842)	Escherichia coli
2	E, F, H, I, K... (A, B, C)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	G, J, M, N (A, B, C, D)	D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE	non-polymer		333.2	4	Chemie (DCS)
4	O, P, Q, R (A, B, C, D)	water	water		18.0	566	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 359 (UniProt: P0A6B4)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	165664.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1909.3
All*	Total formula weight	167574.3

*Water molecules are not included.