2RIO
Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation of non-conventional splicing
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 434 | 50038.4 | 2 | UniProt (P32361) Pfam (PF00069) Pfam (PF06479) In PDB | Saccharomyces cerevisiae (baker's yeast) | Endoplasmic reticulum-to-nucleus signaling 1, Serine/threonine-protein kinase, Endoribonuclease |
2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A, B | STRONTIUM ION | non-polymer | 87.6 | 2 | Chemie (SR) | |||
4 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 100076.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1078.3 | |
All* | Total formula weight | 101155.0 |