Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006397 | biological_process | mRNA processing |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0030968 | biological_process | endoplasmic reticulum unfolded protein response |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006397 | biological_process | mRNA processing |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0030968 | biological_process | endoplasmic reticulum unfolded protein response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1102 |
| Chain | Residue |
| A | ASN145 |
| A | ASP171 |
| A | ADP1101 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SR A 1103 |
| Chain | Residue |
| A | ASP171 |
| A | ADP1101 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 2102 |
| Chain | Residue |
| B | ASN145 |
| B | ASP171 |
| B | ADP2101 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SR B 2103 |
| Chain | Residue |
| B | ADP2101 |
| B | ASP171 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP A 1101 |
| Chain | Residue |
| A | GLY24 |
| A | TYR25 |
| A | GLY26 |
| A | SER27 |
| A | THR30 |
| A | VAL32 |
| A | ALA43 |
| A | LYS45 |
| A | LEU88 |
| A | GLU89 |
| A | CYS91 |
| A | ASN94 |
| A | GLN144 |
| A | ASN145 |
| A | LEU147 |
| A | ASP171 |
| A | MG1102 |
| A | SR1103 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP B 2101 |
| Chain | Residue |
| B | GLY24 |
| B | TYR25 |
| B | GLY26 |
| B | SER27 |
| B | THR30 |
| B | VAL32 |
| B | ALA43 |
| B | LYS45 |
| B | ILE72 |
| B | GLU89 |
| B | CYS91 |
| B | ASN94 |
| B | GLN144 |
| B | ASN145 |
| B | LEU147 |
| B | ASP171 |
| B | MG2102 |
| B | SR2103 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpqNILV |
| Chain | Residue | Details |
| A | ILE136-VAL148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18191223","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2RIO","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP140 | |
| A | GLN144 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASP140 | |
| B | GLN144 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS142 | |
| A | ASP140 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | LYS142 | |
| B | ASP140 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS142 | |
| A | THR195 | |
| A | ASP140 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | LYS142 | |
| B | THR195 | |
| B | ASP140 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | LYS142 | |
| A | ASN145 | |
| A | ASP140 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | LYS142 | |
| B | ASN145 | |
| B | ASP140 | |
