2RGP
Structure of EGFR in complex with hydrazone, a potent dual inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 315 | 36070.8 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (Human) | Receptor tyrosine-protein kinase ErbB-1 |
| 2 | B, C (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D (A) | N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]-5-[(piperidin-1-ylamino)methyl]pyrimidine-4,6-diamine | non-polymer | 446.5 | 1 | Chemie (HYZ) | |||
| 4 | E (A) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36070.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 636.5 | |
| All* | Total formula weight | 36707.3 |
