2R6N

Crystal structure of a pyrrolopyrimidine inhibitor in complex with human Cathepsin K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cathepsin K	polymer	217	23737.7	1	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (human)	Cathepsin O, Cathepsin X, Cathepsin O2
2	A	1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine	non-polymer		418.6	1	Chemie (CKE)
3		water	water		18.0	143	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23737.7
Non-Polymers*	Number of molecules	1
	Total formula weight	418.6
All*	Total formula weight	24156.3

*Water molecules are not included.