2R40
Crystal structure of 20E bound EcR/USP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D | Ecdysone Receptor | polymer | 266 | 30369.0 | 1 | UniProt (O18473) Pfam (PF00104) In PDB | Heliothis virescens (tobacco budworm) | Ecdysteroid receptor; 20-hydroxy-ecdysone receptor; 20E receptor; EcRH; HvEcR |
2 | A | Ultraspiracle | polymer | 263 | 29951.8 | 1 | UniProt (Q7SIF6) Pfam (PF00104) In PDB | Heliothis virescens (tobacco budworm) | Gene regulation protein |
3 | D | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
4 | D | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | D | (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one | non-polymer | 480.6 | 1 | Chemie (20E) | |||
6 | D | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | A | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 1 | Chemie (EPH) | |||
8 | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
D: 284 - 532 (UniProt: O18473)
A: 205 - 466 (UniProt: Q7SIF6)
PDB | External Database | Details |
---|---|---|
Gly 267 | - | expression tag |
Ser 268 | - | expression tag |
His 269 | - | expression tag |
Met 270 | - | expression tag |
Ala 271 | - | expression tag |
Ser 272 | - | expression tag |
Thr 274 | - | expression tag |
Gly 275 | - | expression tag |
Gly 276 | - | expression tag |
Gln 277 | - | expression tag |
Met 279 | - | expression tag |
Gly 280 | - | expression tag |
Asp 282 | - | expression tag |
Pro 283 | - | expression tag |
Gln 321 | - | SEE REMARK 999 |
Thr 322 | - | SEE REMARK 999 |
Trp 323 | - | SEE REMARK 999 |
Cys 483 | Gly 501 | SEE REMARK 999 |
Lys 489 | Glu 507 | SEE REMARK 999 |
PDB | External Database | Details |
---|---|---|
Met 204 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60320.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1567.8 | |
All* | Total formula weight | 61888.5 |