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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

2R40

Crystal structure of 20E bound EcR/USP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)		Ecdysone Receptorpolymer26630369.01UniProt (O18473)Heliothis virescens (tobacco budworm)Ecdysteroid receptor; 20-hydroxy-ecdysone receptor; 20E receptor; EcRH; HvEcR
2B
(A)		Ultraspiraclepolymer26329951.81UniProt (Q7SIF6)Heliothis virescens (tobacco budworm)Gene regulation protein
3C
(D)		CITRATE ANIONnon-polymer189.11Chemie (FLC)
PubChem (31348)
4D
(D)		SULFATE IONnon-polymer96.11Chemie (SO4)
5E
(D)		(2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-onenon-polymer480.61Chemie (20E)
PubChem (16395231)
PubChem (16401465)
PubChem (16757637)
PubChem (20831660)
PubChem (21590111)
PubChem (25421101)
PubChem (25565820)
PubChem (25565823)
PubChem (25565830)
PubChem (25749233)
PubChem (27545171)
PubChem (27545172)
PubChem (40922395)
PubChem (21362)
PubChem (44143979)
PubChem (44231239)
PubChem (44231358)
PubChem (44231483)
PubChem (44658312)
PubChem (18394232)
PubChem (21590113)
PubChem (25421098)
PubChem (54115616)
PubChem (54115617)
PubChem (57001583)
PubChem (271605)
PubChem (57368337)
PubChem (57988720)
PubChem (45107113)
PubChem (439770)
PubChem (66509028)
PubChem (67710993)
PubChem (68490880)
PubChem (69718063)
PubChem (70679502)
PubChem (70686927)
PubChem (51690439)
PubChem (51650479)
PubChem (53298401)
PubChem (71773515)
PubChem (54115615)
PubChem (3032482)
PubChem (73755764)
PubChem (5316997)
PubChem (5459151)
PubChem (5316023)
PubChem (5459840)
PubChem (118701161)
PubChem (124303823)
PubChem (124903270)
PubChem (124903268)
PubChem (124904288)
PubChem (129668839)
PubChem (10767085)
PubChem (11081347)
PubChem (11123671)
PubChem (6708786)
PubChem (101778163)
PubChem (102332533)
PubChem (118856476)
PubChem (7118526)
PubChem (11784921)
PubChem (12304164)
PubChem (10457883)
PubChem (124512252)
PubChem (11386092)
PubChem (12304165)
PubChem (12304169)
PubChem (124897994)
PubChem (124903269)
PubChem (124903271)
PubChem (124904289)
PubChem (124904290)
PubChem (124904291)
PubChem (162880592)
PubChem (162880593)
PubChem (162880591)
PubChem (125462799)
PubChem (129010434)
PubChem (129316840)
PubChem (130386175)
PubChem (132005456)
PubChem (134402098)
PubChem (137950308)
PubChem (138107217)
PubChem (139291981)
PubChem (146159104)
PubChem (162880586)
PubChem (162880587)
PubChem (162880588)
PubChem (162880589)
PubChem (162880590)
PubChem (162880594)
PubChem (163807315)
PubChem (163898140)
PubChem (171319977)
6F
(D)		GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
7G
(A)		L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINEnon-polymer709.91Chemie (EPH)
PubChem (46936564)
PubChem (4474776)
PubChem (5288167)
PubChem (6323300)
PubChem (168313614)
8H, I
(D, A)		waterwater18.085Chemie (HOH)
Sequence modifications
D: 284 - 532 (UniProt: O18473)
PDBExternal DatabaseDetails
Gly 267-expression tag
Ser 268-expression tag
His 269-expression tag
Met 270-expression tag
Ala 271-expression tag
Ser 272-expression tag
Thr 274-expression tag
Gly 275-expression tag
Gly 276-expression tag
Gln 277-expression tag
Met 279-expression tag
Gly 280-expression tag
Asp 282-expression tag
Pro 283-expression tag
Gln 321-SEE REMARK 999
Thr 322-SEE REMARK 999
Trp 323-SEE REMARK 999
Cys 483Gly 501SEE REMARK 999
Lys 489Glu 507SEE REMARK 999
A: 205 - 466 (UniProt: Q7SIF6)
PDBExternal DatabaseDetails
Met 204-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60320.7
Non-Polymers*Number of molecules5
Total formula weight1567.8
All*Total formula weight61888.5
*Water molecules are not included.

253389

PDB entries from 2026-05-13

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