2R40
Crystal structure of 20E bound EcR/USP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003707 | molecular_function | nuclear steroid receptor activity |
A | 0005515 | molecular_function | protein binding |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0008270 | molecular_function | zinc ion binding |
A | 0030518 | biological_process | nuclear receptor-mediated steroid hormone signaling pathway |
D | 0003677 | molecular_function | DNA binding |
D | 0004879 | molecular_function | nuclear receptor activity |
D | 0005634 | cellular_component | nucleus |
D | 0006355 | biological_process | regulation of DNA-templated transcription |
D | 0035076 | biological_process | ecdysone receptor signaling pathway |
D | 0035100 | molecular_function | ecdysone binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE FLC D 9400 |
Chain | Residue |
D | GLY359 |
D | TYR464 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 D 1327 |
Chain | Residue |
D | THR291 |
D | ASN293 |
D | TYR464 |
site_id | AC3 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE 20E D 9001 |
Chain | Residue |
D | THR346 |
D | MET380 |
D | ARG383 |
D | ARG387 |
D | LEU396 |
D | PHE397 |
D | ALA398 |
D | TYR408 |
D | VAL416 |
D | LEU420 |
D | ASN504 |
D | TRP526 |
D | HOH9517 |
D | GLU309 |
D | GLN310 |
D | MET342 |
D | THR343 |
site_id | AC4 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE EPH A 600 |
Chain | Residue |
A | VAL238 |
A | PRO239 |
A | PHE242 |
A | LEU249 |
A | ASN287 |
A | LEU291 |
A | SER335 |
A | GLN338 |
A | ALA339 |
A | GLY340 |
A | VAL341 |
A | PHE345 |
A | SER431 |
A | HIS434 |
A | HOH613 |
A | HOH624 |
site_id | AC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE GOL D 9500 |
Chain | Residue |
D | HOH9544 |