2R37
Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutathione peroxidase 3 | polymer | 207 | 23550.8 | 2 | UniProt (P22352) Pfam (PF00255) In PDB | Homo sapiens (human) | GSHPx-3, GPx-3, Plasma glutathione peroxidase, GSHPx-P, Extracellular glutathione peroxidase, GPx-P |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | water | water | 18.0 | 406 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 223 (UniProt: P22352)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | initiating methionine |
| Gly 73 | Cys 73 | engineered mutation |
| Ala 224 | - | expression tag |
| Glu 225 | - | expression tag |
| Asn 226 | - | expression tag |
| Leu 227 | - | expression tag |
| Tyr 228 | - | expression tag |
| Phe 229 | - | expression tag |
| Gln 230 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47101.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 116.9 | |
| All* | Total formula weight | 47218.6 |
