2R2L
Structure of Farnesyl Protein Transferase bound to PB-93
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyltransferase subunit alpha | polymer | 315 | 37916.6 | 1 | UniProt (Q5RKJ4) Pfam (PF01239) UniProt (by SIFTS) (Q04631) | Rattus norvegicus (Norway rat) | |
| 2 | B (B) | Farnesyltransferase subunit beta | polymer | 401 | 44879.3 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (Norway rat) | CAAX farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, FTase-beta |
| 3 | C (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 5 | E (B) | methyl 4-{[{(3S)-6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}(pyridin-2-ylsulfonyl)amino]methyl}piperidine-1-carboxylate | non-polymer | 563.7 | 1 | Chemie (PB9) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 534 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82795.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1011.4 | |
| All* | Total formula weight | 83807.3 |
