2QYL
Crystal structure of PDE4B2B in complex with inhibitor NPV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphodiesterase 4B, cAMP-specific | polymer | 337 | 38849.0 | 1 | UniProt (Q5T3Z8) Pfam (PF00233) UniProt (by SIFTS) (Q07343) | Homo sapiens (human) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid | non-polymer | 371.3 | 1 | Chemie (NPV) | |||
| 5 | F (A) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A: 152 - 487 (UniProt: Q5T3Z8)
| PDB | External Database | Details |
|---|---|---|
| Met 151 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38849.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 485.4 | |
| All* | Total formula weight | 39334.4 |
