2QYI
Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cationic trypsin | polymer | 223 | 23324.3 | 2 | UniProt (P00760) Pfam (PF00089) | Bos taurus (bovine) | Beta-trypsin |
| 2 | B, D (B, D) | Chymotrypsin inhibitor 3 | polymer | 183 | 20310.9 | 2 | UniProt (P10822) Pfam (PF00197) | Psophocarpus tetragonolobus (Goa bean) | WCI-3 |
| 3 | E, G (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | F (B) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
B, D: 604 - 786 (UniProt: P10822)
| PDB | External Database | Details |
|---|---|---|
| Arg 668 | Leu 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87270.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 138.8 | |
| All* | Total formula weight | 87409.2 |
