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2QWR

Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP intact form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHeat shock cognate 71 kDa proteinpolymer39443368.11UniProt (P19120)
Pfam (PF00012)
In PDB
Bos taurus (cattle)Heat shock 70 kDa protein 8
2BPutative tyrosine-protein phosphatase auxilinpolymer9210747.51UniProt (Q27974)
In PDB
Bos taurus (cattle)DnaJ homolog subfamily C member 6
3APHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4AACETIC ACIDnon-polymer60.11Chemie (ACY)
5AGLYCEROLnon-polymer92.12Chemie (GOL)
6waterwater18.0105Chemie (HOH)
Sequence modifications
A: 1 - 394 (UniProt: P19120)
PDBExternal DatabaseDetails
Cys 171Arg 171engineered mutation
B: 813 - 904 (UniProt: Q27974)
PDBExternal DatabaseDetails
Cys 876Asp 876engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54115.5
Non-Polymers*Number of molecules4
Total formula weight750.4
All*Total formula weight54866.0
*Water molecules are not included.

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PDB entries from 2024-07-24

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