2QWQ
Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock cognate 71 kDa protein | polymer | 394 | 43368.1 | 1 | UniProt (P19120) Pfam (PF00012) | Bos taurus (cattle) | Heat shock 70 kDa protein 8 |
| 2 | B (B) | Putative tyrosine-protein phosphatase auxilin | polymer | 92 | 10747.5 | 1 | UniProt (Q27974) | Bos taurus (cattle) | DnaJ homolog subfamily C member 6 |
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 6 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H, I (A, B) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1 - 394 (UniProt: P19120)
B: 813 - 904 (UniProt: Q27974)
| PDB | External Database | Details |
|---|---|---|
| Cys 171 | Arg 171 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 876 | Asp 876 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54115.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 766.4 | |
| All* | Total formula weight | 54882.0 |
