2QWQ
Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock cognate 71 kDa protein | polymer | 394 | 43368.1 | 1 | UniProt (P19120) Pfam (PF00012) In PDB | Bos taurus (cattle) | Heat shock 70 kDa protein 8 |
2 | B | Putative tyrosine-protein phosphatase auxilin | polymer | 92 | 10747.5 | 1 | UniProt (Q27974) In PDB | Bos taurus (cattle) | DnaJ homolog subfamily C member 6 |
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
5 | A | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1 - 394 (UniProt: P19120)
B: 813 - 904 (UniProt: Q27974)
PDB | External Database | Details |
---|---|---|
Cys 171 | Arg 171 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Cys 876 | Asp 876 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54115.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 766.4 | |
All* | Total formula weight | 54882.0 |