2QUJ
Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tryptophanyl-tRNA synthetase | polymer | 477 | 54060.1 | 2 | UniProt (P23381) Pfam (PF00458) Pfam (PF00579) In PDB | Homo sapiens (human) | Tryptophan-tRNA ligase, TrpRS, Interferon-induced protein 53, IFP53, hWRS |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 3 | A | TRYPTOPHANYL-5'AMP | non-polymer | 533.4 | 1 | Chemie (TYM) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | B | TRYPTOPHAN | non-polymer | 204.2 | 1 | Chemie (TRP) | |||
| 6 | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 471 (UniProt: P23381)
| PDB | External Database | Details |
|---|---|---|
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108120.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1425.1 | |
| All* | Total formula weight | 109545.3 |
