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2QUJ

Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tryptophanyl-tRNA synthetasepolymer47754060.12UniProt (P23381)
Pfam (PF00458)
Pfam (PF00579)
Homo sapiens (human)Tryptophan-tRNA ligase, TrpRS, Interferon-induced protein 53, IFP53, hWRS
2C, D, E, F, G...
(A, B)
CHLORIDE IONnon-polymer35.59Chemie (CL)
3H
(A)
TRYPTOPHANYL-5'AMPnon-polymer533.41Chemie (TYM)
4I, J, P, Q
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
5O
(B)
TRYPTOPHANnon-polymer204.21Chemie (TRP)
6R, S
(A, B)
waterwater18.0198Chemie (HOH)
Sequence modifications
A, B: 1 - 471 (UniProt: P23381)
PDBExternal DatabaseDetails
His 472-expression tag
His 473-expression tag
His 474-expression tag
His 475-expression tag
His 476-expression tag
His 477-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight108120.2
Non-Polymers*Number of molecules15
Total formula weight1425.1
All*Total formula weight109545.3
*Water molecules are not included.

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PDB entries from 2026-02-25

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