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2QRE

Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranotide (ZMP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, C)
SNF1-like protein kinase ssp2polymer13715903.42UniProt (O74536)
Pfam (PF16579)
Schizosaccharomyces pombe (fission yeast)
2B, E
(B, D)
SPCC1919.03c proteinpolymer9710865.32UniProt (P78789)
Pfam (PF04739)
Schizosaccharomyces pombe (fission yeast)
3C, F
(G, E)
Protein C1556.08cpolymer33437436.12UniProt (Q10343)
Pfam (PF00571)
Schizosaccharomyces pombe (fission yeast)
4G, H
(G, E)
AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDEnon-polymer338.22Chemie (AMZ)
5I, J, K, L, M...
(A, B, G, C, D...)
waterwater18.019Chemie (HOH)
Sequence modifications
B, D: 203 - 298 (UniProt: P78789)
PDBExternal DatabaseDetails
Met 202-expression tag
G, E: 3 - 334 (UniProt: Q10343)
PDBExternal DatabaseDetails
Ala 1-expression tag
Met 2-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight128409.7
Non-Polymers*Number of molecules2
Total formula weight676.4
All*Total formula weight129086.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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