2QRA

Crystal structure of XIAP BIR1 domain (P21 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, C, B, A)	Baculoviral IAP repeat-containing protein 4	polymer	111	12386.8	4	UniProt (P98170) Pfam (PF00653)	Homo sapiens (human)	X-linked inhibitor of apoptosis; XIAP; Inhibitor of apoptosis protein 3; X-linked IAP; IAP-like protein; HILP
2	E, G, K, L (D, C, B, A)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	F, H, I, J, M... (D, C, A)	ETHANOL	non-polymer		46.1	6	Chemie (EOH)
4	O, P, Q, R (D, C, B, A)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

D, C, B, A: 3010 - 3099 (UniProt: P98170)

PDB	External Database	Details
Met 2989	-	expression tag
Gly 2990	-	expression tag
Ser 2991	-	expression tag
Ser 2992	-	expression tag
His 2993	-	expression tag
His 2994	-	expression tag
His 2995	-	expression tag
His 2996	-	expression tag
His 2997	-	expression tag
His 2998	-	expression tag
Ser 2999	-	expression tag
Ser 3000	-	expression tag
Gly 3001	-	expression tag
Leu 3002	-	expression tag
Val 3003	-	expression tag
Pro 3004	-	expression tag
Arg 3005	-	expression tag
Gly 3006	-	expression tag
Ser 3007	-	expression tag
His 3008	-	expression tag
Met 3009	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49547.2
Non-Polymers*	Number of molecules	10
	Total formula weight	538.0
All*	Total formula weight	50085.2

*Water molecules are not included.