2QQO

Crystal Structure of the a2b1b2 Domains from Human Neuropilin-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Neuropilin-2	polymer	460	51937.3	2	UniProt (O60462) Pfam (PF00431) Pfam (PF00754)	Homo sapiens (human)	Vascular endothelial cell growth factor 165 receptor 2
2	C, F (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, G, H, I, J... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	E (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
5	L, M (A, B)	water	water		18.0	365	Chemie (HOH)

Sequence modifications

A, B: 145 - 595 (UniProt: O60462)

PDB	External Database	Details
Ala 142	-	expression tag
Asp 143	-	expression tag
Pro 144	-	expression tag
His 596	-	expression tag
His 597	-	expression tag
His 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag
His 601	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103874.6
Non-Polymers*	Number of molecules	9
	Total formula weight	574.7
All*	Total formula weight	104449.3

*Water molecules are not included.