2QP4
Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bile salt sulfotransferase | polymer | 284 | 33774.6 | 1 | UniProt (Q06520) Pfam (PF00685) In PDB | Homo sapiens (human) | Hydroxysteroid Sulfotransferase, HST, Dehydroepiandrosterone sulfotransferase, DHEA-ST, ST2, ST2A3 |
2 | A | (3Beta,5alpha)-3-Hydroxyandrostan-17-one | non-polymer | 290.4 | 1 | Chemie (AOX) |
Sequence modifications
A: 2 - 285 (UniProt: Q06520)
PDB | External Database | Details |
---|---|---|
Trp 137 | Met 137 | engineered mutation |
Thr 243 | Ala 243 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33774.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 290.4 | |
All* | Total formula weight | 34065.1 |