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2QP4

Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABile salt sulfotransferasepolymer28433774.61UniProt (Q06520)
Pfam (PF00685)
In PDB
Homo sapiens (human)Hydroxysteroid Sulfotransferase, HST, Dehydroepiandrosterone sulfotransferase, DHEA-ST, ST2, ST2A3
2A(3Beta,5alpha)-3-Hydroxyandrostan-17-onenon-polymer290.41Chemie (AOX)
Sequence modifications
A: 2 - 285 (UniProt: Q06520)
PDBExternal DatabaseDetails
Trp 137Met 137engineered mutation
Thr 243Ala 243conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33774.6
Non-Polymers*Number of molecules1
Total formula weight290.4
All*Total formula weight34065.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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