2QOK
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin receptor | polymer | 373 | 41915.9 | 1 | UniProt (Q6P4R6) Pfam (PF14575) Pfam (PF07714) Pfam (PF07647) UniProt (by SIFTS) (P29320) | Homo sapiens (human) | |
| 2 | B (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 3 | C (A) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
A: 577 - 947 (UniProt: Q6P4R6)
| PDB | External Database | Details |
|---|---|---|
| Gly 575 | - | expression tag |
| Ser 576 | - | expression tag |
| Phe 596 | Tyr 596 | engineered mutation |
| Phe 602 | Tyr 602 | engineered mutation |
| Ala 768 | Ser 768 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41915.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 78.1 | |
| All* | Total formula weight | 41994.0 |
