2QOH
Crystal Structure of Abl kinase bound with PPY-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 288 | 33242.0 | 2 | UniProt (P00520) Pfam (PF07714) | Mus musculus (house mouse) | p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1, Abl kinase |
| 2 | C, D (A, B) | 5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE | non-polymer | 372.4 | 2 | Chemie (P3Y) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A, B: 229 - 515 (UniProt: P00520)
| PDB | External Database | Details |
|---|---|---|
| Gly 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66483.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 744.8 | |
| All* | Total formula weight | 67228.8 |
