2QO3

Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	EryAII Erythromycin polyketide synthase modules 3 and 4	polymer	915	96689.2	2	UniProt (A4F7P0) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) UniProt (by SIFTS) (Q03132)	Saccharopolyspora erythraea	6 Deoxyerythronolide B Synthase
2	C, F (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
3	D, G (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	E, H (A, B)	(2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE	non-polymer		225.3	2	Chemie (CER)
5	I, J (A, B)	water	water		18.0	194	Chemie (HOH)

Sequence modifications

A, B: 27 - 922 (UniProt: A4F7P0)

PDB	External Database	Details
Met 26	-	initiating methionine
Ser 923	-	expression tag
Ser 924	-	expression tag
Ser 925	-	expression tag
Val 926	-	expression tag
Asp 927	-	expression tag
Lys 928	-	expression tag
Leu 929	-	expression tag
Ala 930	-	expression tag
Ala 931	-	expression tag
Ala 932	-	expression tag
Leu 933	-	expression tag
Glu 934	-	expression tag
His 935	-	expression tag
His 936	-	expression tag
His 937	-	expression tag
His 938	-	expression tag
His 939	-	expression tag
His 940	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	193378.4
Non-Polymers*	Number of molecules	6
	Total formula weight	639.6
All*	Total formula weight	194017.9

*Water molecules are not included.