2QNY
Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and SS-(2-hydroxyethyl) O-decyl ester carbono(dithioperoxoic) acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | polymer | 335 | 34979.5 | 2 | UniProt (P0A574) Pfam (PF08545) Pfam (PF08541) UniProt (by SIFTS) (P9WNG3) | Mycobacterium tuberculosis | 3-oxoacyl- [acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, MtFabH |
| 2 | C, F (A, B) | DECYL FORMATE | non-polymer | 186.3 | 2 | Chemie (DFD) | |||
| 3 | D, E, G (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 443 | Chemie (HOH) |
Sequence modifications
A, B: -10 - 318 (UniProt: P0A574)
| PDB | External Database | Details |
|---|---|---|
| Phe 246 | Ala 260 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69959.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 607.0 | |
| All* | Total formula weight | 70565.9 |
