2QMJ
Crystral Structure of the N-terminal Subunit of Human Maltase-Glucoamylase in Complex with Acarbose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Maltase-glucoamylase, intestinal | polymer | 870 | 98586.0 | 1 | UniProt (O43451) Pfam (PF00088) Pfam (PF13802) Pfam (PF01055) Pfam (PF21365) In PDB | Homo sapiens (human) | |
| 2 | X | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | B | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 645.6 | 1 | In PDB BIRD (PRD_900007) GlyTouCan (G66431MI) | alpha-acarbose | ||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 6 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 626 | Chemie (HOH) |
Sequence modifications
A: 1 - 868 (UniProt: O43451)
| PDB | External Database | Details |
|---|---|---|
| Ala 869 | - | expression tag |
| His 870 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 98586.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1070.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1367.3 | |
| All* | Total formula weight | 101023.3 |
