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2QL2

Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Transcription factor E2-alphapolymer607141.42Pfam (PF00010)
UniProt (by SIFTS) (P15806)
Mus musculus (Mouse)
2B, D
(B, D)
Neurogenic differentiation factor 1polymer606986.22UniProt (Q60867)
Pfam (PF00010)
Mus musculus (mouse)NeuroD1
3E, G
(E, G)
DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3')polymer164865.22
4F, H
(F, H)
DNA (5'-D(*DAP*DGP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DTP*DGP*DGP*DCP*DCP*DTP*DA)-3')polymer164932.22
5I, J, K, L, M...
(A, B, C, E, F...)
waterwater18.041Chemie (HOH)
Sequence modifications
B, D: 102 - 160 (UniProt: Q60867)
PDBExternal DatabaseDetails
Ser 101-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight47849.9
All*Total formula weight47849.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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