2QKY
complex structure of dipeptidyl peptidase IV and a oxadiazolyl ketone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) (Dipeptidyl peptidase 4 soluble form) (Dipeptidyl peptidase IV soluble form) | polymer | 728 | 84476.6 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (Human) | |
| 2 | E, F, G, H (A, B, C, D) | 2-[(2-{(2S,4S)-2-[(R)-(5-tert-butyl-1,3,4-oxadiazol-2-yl)(hydroxy)methyl]-4-fluoropyrrolidin-1-yl}-2-oxoethyl)amino]-2-methylpropan-1-ol | non-polymer | 372.4 | 4 | Chemie (13Z) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 40 - 766 (UniProt: P27487)
| PDB | External Database | Details |
|---|---|---|
| Thr 39 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 337906.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1489.7 | |
| All* | Total formula weight | 339396.3 |
