2QJ4
A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hepatocyte growth factor | polymer | 184 | 21208.1 | 2 | UniProt (Q08048) Pfam (PF00024) Pfam (PF00051) | Mus musculus (house mouse) | |
| 2 | C, D, E (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 210 (UniProt: Q08048)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42416.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 42704.5 |
