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2QG4

Crystal structure of human UDP-glucose dehydrogenase product complex with UDP-glucuronate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...UDP-glucose 6-dehydrogenasepolymer46752083.48UniProt (O60701)
Pfam (PF03721)
Pfam (PF00984)
Pfam (PF03720)
In PDB
Homo sapiens (human)UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH
2F, G, A, H, B...NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.48Chemie (NAD)
3F, G, A, H, B...URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACIDnon-polymer580.38Chemie (UGA)
4H, B, D, FCHLORIDE IONnon-polymer35.58Chemie (CL)
5F, G, B, C1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
6waterwater18.02999Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 466 (UniProt: O60701)
PDBExternal DatabaseDetails
Ser 0-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight416667.3
Non-Polymers*Number of molecules28
Total formula weight10481.6
All*Total formula weight427148.9
*Water molecules are not included.

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PDB entries from 2024-07-24

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