2QE2

Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	RNA-directed RNA polymerase	polymer	578	64247.6	2	UniProt (Q99AU2) Pfam (PF00998) In PDB	Hepatitis C virus subtype 1b	NS5B, p68
2	A, B	2-{[N-(2-ACETYL-5-CHLORO-4-FLUOROPHENYL)GLYCYL]AMINO}BENZOIC ACID	non-polymer		364.8	2	Chemie (452)

Sequence modifications

A, B: 1 - 570 (UniProt: Q99AU2)

PDB	External Database	Details
Gly 571	-	expression tag
Ser 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128495.2
Non-Polymers*	Number of molecules	2
	Total formula weight	729.5
All*	Total formula weight	129224.7

*Water molecules are not included.