2QCH
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Uridine 5'-monophosphate synthase (UMP synthase) | polymer | 260 | 28299.7 | 2 | UniProt (P11172) Pfam (PF00215) In PDB | Homo sapiens (human) | |
| 2 | A, B | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 3 | A, B | 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 434.1 | 2 | Chemie (5IU) | |||
| 4 | A, B | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 5 | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
A, B: 224 - 480 (UniProt: P11172)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | - | expression tag |
| Ala 222 | - | expression tag |
| Met 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56599.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1738.3 | |
| All* | Total formula weight | 58337.8 |
