2QCG

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Uridine 5'-monophosphate synthase (UMP synthase)	polymer	260	28299.7	2	UniProt (P11172) Pfam (PF00215)	Homo sapiens (human)
2	C, D (A, B)	5-BROMO-URIDINE-5'-MONOPHOSPHATE	non-polymer		403.1	2	Chemie (5BU)
3	E, F (A, B)	water	water		18.0	137	Chemie (HOH)

Sequence modifications

A, B: 224 - 480 (UniProt: P11172)

PDB	External Database	Details
Gly 221	-	expression tag
Ala 222	-	expression tag
Met 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56599.5
Non-Polymers*	Number of molecules	2
	Total formula weight	806.2
All*	Total formula weight	57405.6

*Water molecules are not included.