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2QCE

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uridine 5'-monophosphate synthase (UMP synthase)polymer26028331.81UniProt (P11172)
Pfam (PF00215)
Homo sapiens (human)
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
waterwater18.0357Chemie (HOH)
Sequence modifications
A: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Gly 221-expression tag
Ala 222-expression tag
Met 223-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28331.8
Non-Polymers*Number of molecules4
Total formula weight315.7
All*Total formula weight28647.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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