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2QCD

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uridine 5'-monophosphate synthase (UMP synthase)polymer26028331.81UniProt (P11172)
Pfam (PF00215)
Homo sapiens (human)
2B
(B)
Uridine 5'-monophosphate synthase (UMP synthase)polymer26028299.71UniProt (P11172)
Pfam (PF00215)
Homo sapiens (human)
3C, D
(A, B)
URIDINE-5'-MONOPHOSPHATEnon-polymer324.22Chemie (U5P)
4E, F
(A, B)
waterwater18.0348Chemie (HOH)
Sequence modifications
A: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Gly 221-expression tag
Ala 222-expression tag
Met 223-expression tag
B: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Gly 221-expression tag
Ala 222-expression tag
Met 223-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56631.6
Non-Polymers*Number of molecules2
Total formula weight648.4
All*Total formula weight57279.9
*Water molecules are not included.

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PDB entries from 2025-07-30

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