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2QBY

Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
DNA (33-MER)polymer3310200.61
2B
(D)
DNA (33-MER)polymer3310093.51
3C
(A)
Cell division control protein 6 homolog 1polymer38643922.91UniProt (Q980N4)
Pfam (PF13401)
Pfam (PF22703)
Pfam (PF09079)
Sulfolobus solfataricusCDC6 homolog 1
4D
(B)
Cell division control protein 6 homolog 3polymer38443468.01UniProt (Q97WM8)
Pfam (PF13401)
Pfam (PF22703)
Pfam (PF09079)
Sulfolobus solfataricusCDC6 homolog 3
5E, F
(C)
SPERMIDINEnon-polymer145.22Chemie (SPD)
6G
(D)
POTASSIUM IONnon-polymer39.11Chemie (K)
7H, J
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
8I, K
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
9L, M
(A, B)
waterwater18.04Chemie (HOH)
Sequence modifications
A: 15 - 397 (UniProt: Q980N4)
PDBExternal DatabaseDetails
Gly 12-expression tag
Ala 13-expression tag
Met 14-expression tag
B: 14 - 394 (UniProt: Q97WM8)
PDBExternal DatabaseDetails
Gly 11-expression tag
Ala 12-expression tag
Met 13-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight107685.0
Non-Polymers*Number of molecules7
Total formula weight1232.6
All*Total formula weight108917.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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