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2QBQ

Crystal structure of ptp1b-inhibitor complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer29934833.71UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
4-BROMO-3-(CARBOXYMETHOXY)-5-{3-[(3,3,5,5-TETRAMETHYLCYCLOHEXYL)AMINO]PHENYL}THIOPHENE-2-CARBOXYLIC ACIDnon-polymer510.41Chemie (4B3)
3C
(A)
waterwater18.0270Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34833.7
Non-Polymers*Number of molecules1
Total formula weight510.4
All*Total formula weight35344.2
*Water molecules are not included.

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PDB entries from 2025-07-30

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