2QB0

Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Transcription factor ETV6	polymer	77	9252.5	2	UniProt (P41212) Pfam (PF02198) In PDB	Homo sapiens	ETS translocation variant 6,ETS-related protein Tel1,Tel
2	B, D	Transcription factor ETV6,Endolysin	polymer	241	27720.8	2	UniProt (P41212) UniProt (P00720) Pfam (PF00959) In PDB	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,Lysis protein,Lysozyme,Muramidase
3	B, C, D	MANGANESE (II) ION	non-polymer		54.9	5	Chemie (MN)
4		water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, C: 15 - 91 (UniProt: P41212)

PDB	External Database	Details
Glu 80	Val 112	engineered mutation

B, D: 15 - 91 (UniProt: P41212)

PDB	External Database	Details
Ala 92	-	linker
Gly 93	-	linker
Pro 94	-	linker

B, D: 95 - 255 (UniProt: P00720)

PDB	External Database	Details
Gly 105	Arg 12	conflict
Thr 147	Cys 54	conflict
Cys 161	Asn 68	conflict
Cys 186	Ala 93	conflict
Ala 190	Cys 97	conflict
Arg 230	Ile 137	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73946.6
Non-Polymers*	Number of molecules	5
	Total formula weight	274.7
All*	Total formula weight	74221.3

*Water molecules are not included.