2Q61
Crystal Structure of PPARgamma ligand binding domain bound to partial agonist SR145
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome Proliferator-Activated Receptor gamma | polymer | 274 | 31295.3 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma |
2 | A, B | 1-BENZYL-5-CHLORO-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID | non-polymer | 393.9 | 2 | Chemie (SF1) | |||
3 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A, B: 205 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Ser 204 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62590.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 787.8 | |
All* | Total formula weight | 63378.4 |