2Q5P
Crystal Structure of PPARgamma bound to partial agonist MRL24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome Proliferator-Activated Receptor gamma | polymer | 274 | 31295.3 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma |
| 2 | C, D (A, B) | (2S)-2-(3-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID | non-polymer | 527.5 | 2 | Chemie (241) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A, B: 205 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Ser 204 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62590.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1055.0 | |
| All* | Total formula weight | 63645.6 |
