2PZI
Crystal Structure of Protein kinase PknG from Mycobacterium tuberculosis in Complex with Tetrahydrobenzothiophene AX20017
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Probable serine/threonine-protein kinase pknG | polymer | 681 | 74183.0 | 2 | UniProt (P65728) Pfam (PF16919) Pfam (PF00069) Pfam (PF16918) UniProt (by SIFTS) (P9WI73) In PDB | Mycobacterium tuberculosis | |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | A, B | CADMIUM ION | non-polymer | 112.4 | 2 | Chemie (CD) | |||
| 4 | A, B | 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE | non-polymer | 264.3 | 2 | Chemie (AXX) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A, B: 73 - 750 (UniProt: P65728)
| PDB | External Database | Details |
|---|---|---|
| Gly 69 | - | cloning artifact |
| Ser 70 | - | cloning artifact |
| His 71 | - | cloning artifact |
| Met 72 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 148366.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1341.5 | |
| All* | Total formula weight | 149707.5 |
