2PXC
Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAM and GTPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)] | polymer | 269 | 30306.9 | 1 | UniProt (P05769) | Murray valley encephalitis virus (strain MVE-1-51) | |
| 2 | B (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | C, D (A) | GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 772.4 | 2 | Chemie (G3A) PubChem (135450590) PubChem (162789443) PubChem (171037886) PubChem (136948342) | |||
| 4 | E (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30306.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1943.2 | |
| All* | Total formula weight | 32250.1 |
