2PXC
Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAM and GTPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)] | polymer | 269 | 30306.9 | 1 | UniProt (P05769) Pfam (PF01728) | Murray valley encephalitis virus (strain MVE-1-51) | |
| 2 | B (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 3 | C, D (A) | GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 772.4 | 2 | Chemie (G3A) | |||
| 4 | E (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30306.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1943.2 | |
| All* | Total formula weight | 32250.1 |
