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2PX4

Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)]polymer26930306.91UniProt (P05769)
Pfam (PF01728)
Murray valley encephalitis virus (strain MVE-1-51)
2B, C, D
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
3E, F, G, H, I...
(A)
SULFATE IONnon-polymer96.17Chemie (SO4)
4L, M, N, O, P...
(A)
UNKNOWN ATOM OR IONnon-polymer9Chemie (UNX)
5U
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
6V
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7W
(A)
waterwater18.0180Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30306.9
Non-Polymers*Number of molecules21
Total formula weight1255.3
All*Total formula weight31562.2
*Water molecules are not included.

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PDB entries from 2025-12-03

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