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2PX2

Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)]polymer26930306.92UniProt (P05769)
Pfam (PF01728)
Murray valley encephalitis virus (strain MVE-1-51)
2C, D, E, G, H...
(A, B)
CHLORIDE IONnon-polymer35.57Chemie (CL)
3F, K
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
4L, M
(A, B)
waterwater18.0333Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60613.7
Non-Polymers*Number of molecules9
Total formula weight1017.0
All*Total formula weight61630.7
*Water molecules are not included.

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PDB entries from 2025-10-15

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