2PUQ
Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Replaces: 2PMMEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Coagulation factor VII | polymer | 94 | 10256.5 | 1 | UniProt (P08709) Pfam (PF00008) Pfam (PF14670) In PDB | Homo sapiens (human) | Serum prothrombin conversion accelerator; SPCA; Proconvertin; Eptacog alfa |
| 2 | H | Coagulation factor VII | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (human) | Serum prothrombin conversion accelerator; SPCA; Proconvertin; Eptacog alfa |
| 3 | T | Tissue factor | polymer | 204 | 23171.8 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) In PDB | Homo sapiens (human) | Soluble tissue factor; TF; Coagulation factor III; Thromboplastin; CD142 antigen |
| 4 | I | TRP-TYR-THR-ARG CHLOROMETHYLKETONE INHIBITOR | polymer | 5 | 660.2 | 1 | BIRD (PRD_000285) | ||
| 5 | L | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 6 | L | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 7 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62191.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 62576.0 |
