2PT9
The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spermidine synthase | polymer | 321 | 36640.5 | 3 | UniProt (Q8II73) Pfam (PF17284) Pfam (PF01564) | Plasmodium falciparum | |
| 2 | D, I, L (A, B, C) | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE | non-polymer | 356.4 | 3 | Chemie (S4M) | |||
| 3 | E, J, M (A, B, C) | cis-4-methylcyclohexanamine | non-polymer | 113.2 | 3 | Chemie (2MH) | |||
| 4 | F, N (A, C) | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | non-polymer | 252.3 | 2 | Chemie (1PG) | |||
| 5 | G, K, O (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | P, Q, R (A, B, C) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 109921.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2285.9 | |
| All* | Total formula weight | 112207.3 |
