2PQF
Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Poly [ADP-ribose] polymerase 12 | polymer | 198 | 22824.0 | 6 | UniProt (Q9H0J9) Pfam (PF00644) | Homo sapiens (human) | PARP-12, Zinc finger CCCH domain-containing protein 1 |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | 3-AMINOBENZOIC ACID | non-polymer | 137.1 | 6 | Chemie (GAB) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | CITRIC ACID | non-polymer | 192.1 | 6 | Chemie (CIT) | |||
| 4 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 489 - 684 (UniProt: Q9H0J9)
| PDB | External Database | Details |
|---|---|---|
| Ser 487 | - | cloning artifact |
| Mse 488 | - | cloning artifact |
| Mse 548 | Met 548 | modified residue |
| Mse 617 | Met 617 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 136943.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1975.6 | |
| All* | Total formula weight | 138919.5 |
