2PQA

Crystal Structure of Full-length Human RPA 14/32 Heterodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Replication protein A 32 kDa subunit	polymer	131	14660.9	2	UniProt (P15927)	Homo sapiens (human)	RP-A, RF-A, Replication factor-A protein 2, p32, p34
2	B, D (B, D)	Replication protein A 14 kDa subunit	polymer	142	16117.5	2	UniProt (P35244) Pfam (PF08661)	Homo sapiens (human)	RP-A, RF-A, Replication factor-A protein 3, p14

Sequence modifications

B, D: 1 - 121 (UniProt: P35244)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	61556.6
All*	Total formula weight	61556.6

*Water molecules are not included.