2PPB
Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G, X | DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3') | polymer | 23 | 7001.5 | 2 | |||
| 2 | H, Y | RNA (5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3') | polymer | 16 | 5184.1 | 2 | |||
| 3 | I, Z | DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3') | polymer | 14 | 4323.8 | 2 | |||
| 4 | A, B, K, L | DNA-directed RNA polymerase alpha chain | polymer | 315 | 35056.2 | 4 | UniProt (Q9Z9H6) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) UniProt (by SIFTS) (Q5SHR6) In PDB | Thermus thermophilus | RNAP alpha subunit, Transcriptase alpha chain, RNA polymerase subunit alpha |
| 5 | C, M | DNA-directed RNA polymerase beta chain | polymer | 1119 | 125436.5 | 2 | UniProt (Q8RQE9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Thermus thermophilus | RNAP beta subunit, Transcriptase beta chain, RNA polymerase subunit beta |
| 6 | D, N | DNA-directed RNA polymerase beta' chain | polymer | 1524 | 170997.4 | 2 | UniProt (Q8RQE8) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Thermus thermophilus | RNAP beta' subunit, Transcriptase beta' chain, RNA polymerase beta' subunit |
| 7 | E, O | DNA-directed RNA polymerase omega chain | polymer | 99 | 11533.3 | 2 | UniProt (Q8RQE7) Pfam (PF01192) In PDB | Thermus thermophilus | RNAP omega subunit, Transcriptase omega chain, RNA polymerase omega subunit |
| 8 | D, N | STREPTOLYDIGIN | non-polymer | 600.7 | 2 | Chemie (STD) | |||
| 9 | D, N | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 10 | N, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 11 | D, M | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 2 | Chemie (APC) | |||
| 12 | water | water | 18.0 | 2470 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 789178.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2570.7 | |
| All* | Total formula weight | 791748.7 |
