2PMW
The Crystal Structure of Proprotein convertase subtilisin kexin type 9 (PCSK9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 126 | 14107.8 | 1 | UniProt (Q5SZQ2) Pfam (PF05922) UniProt (by SIFTS) (Q8NBP7) | Homo sapiens (human) | Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1 |
| 2 | B (B) | Proprotein convertase subtilisin/kexin type 9 | polymer | 540 | 57357.6 | 1 | UniProt (Q5SZQ2) Pfam (PF00082) Pfam (PF18459) Pfam (PF18464) Pfam (PF18463) UniProt (by SIFTS) (Q8NBP7) | Homo sapiens (human) | |
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 31 - 152 (UniProt: Q5SZQ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | cloning artifact |
| Ala 28 | - | cloning artifact |
| Met 29 | - | cloning artifact |
| Gly 30 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71465.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 71657.6 |
