2PMF
The crystal structure of a human glycyl-tRNA synthetase mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycyl-tRNA synthetase | polymer | 693 | 78805.0 | 1 | UniProt (P41250) Pfam (PF00458) Pfam (PF00587) Pfam (PF03129) | Homo sapiens (human) | Glycine--tRNA ligase, GlyRS |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A: 1 - 685 (UniProt: P41250)
| PDB | External Database | Details |
|---|---|---|
| Arg 526 | Gly 580 | engineered mutation |
| Leu 686 | - | cloning artifact |
| Glu 687 | - | cloning artifact |
| His 688 | - | cloning artifact |
| His 689 | - | cloning artifact |
| His 690 | - | cloning artifact |
| His 691 | - | cloning artifact |
| His 692 | - | cloning artifact |
| His 693 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 78805.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 127.5 | |
| All* | Total formula weight | 78932.5 |
