2PL0
LCK bound to imatinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proto-oncogene tyrosine-protein kinase LCK | polymer | 289 | 33399.1 | 1 | UniProt (P06239) Pfam (PF07714) In PDB | Homo sapiens (human) | p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell- specific protein-tyrosine kinase |
| 2 | A | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | non-polymer | 493.6 | 1 | Chemie (STI) | |||
| 3 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 225 - 509 (UniProt: P06239)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | - | expression tag |
| Ser 222 | - | expression tag |
| His 223 | - | expression tag |
| Met 224 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33399.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 493.6 | |
| All* | Total formula weight | 33892.7 |
