Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

2PL0

LCK bound to imatinib

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proto-oncogene tyrosine-protein kinase LCKpolymer28933399.11UniProt (P06239)
Pfam (PF07714)
Homo sapiens (human)p56-LCK, Lymphocyte cell-specific protein-tyrosine kinase, LSK, T cell- specific protein-tyrosine kinase
2B
(A)
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDEnon-polymer493.61Chemie (STI)
3C
(A)
waterwater18.093Chemie (HOH)
Sequence modifications
A: 225 - 509 (UniProt: P06239)
PDBExternal DatabaseDetails
Gly 221-expression tag
Ser 222-expression tag
His 223-expression tag
Met 224-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33399.1
Non-Polymers*Number of molecules1
Total formula weight493.6
All*Total formula weight33892.7
*Water molecules are not included.

243083

PDB entries from 2025-10-15

PDB statisticsPDBj update infoContact PDBjnumon