2PK3

Crystal Structure of a GDP-4-keto-6-deoxy-D-mannose reductase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GDP-6-deoxy-D-lyxo-4-hexulose reductase	polymer	321	36001.1	2	UniProt (Q6T1X6) Pfam (PF16363)	Aneurinibacillus thermoaerophilus
2	C, E (A, B)	[(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4R,5R)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE	non-polymer		639.3	2	Chemie (A2R)
3	D, F (A, B)	GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE	non-polymer		605.3	2	Chemie (GDD)
4	G, H (A, B)	water	water		18.0	350	Chemie (HOH)

Sequence modifications

A, B: 1 - 309 (UniProt: Q6T1X6)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72002.3
Non-Polymers*	Number of molecules	4
	Total formula weight	2489.3
All*	Total formula weight	74491.5

*Water molecules are not included.